Skip to content
The Weight Clinic
The Weight Clinic blog

Real talk, plainly written.

Articles on Mounjaro, Wegovy, GLP-1 side effects, dose escalation, food and lifestyle — and everything else worth knowing about weight-loss medication in the UK.

·
31 August 2026

Starting Foundayo (orforglipron): the 0.8mg and 2.5mg stages

Foundayo (orforglipron) starts at 0.8mg once daily and steps up to 2.5mg. What each stage involves, why titration is gradual, and how to take a small-molecule GLP-1 tablet.

Read article
A once-daily oral weight-management tablet with a glass of water on a plain surface
29 August 2026

Will Foundayo Be Available on the NHS?

Will Foundayo (orforglipron) be on the NHS? No NICE date is confirmed. Here's how NHS funding decisions work and what its UK licence means.

Read article
A weight-loss tablet beside an injection pen on a plain surface, illustrating a cost comparison
28 August 2026

Will Orforglipron Cost Less Than Weight-Loss Injections?

Will orforglipron (Foundayo) cost less than weight-loss injections in the UK? An honest look at what we know, what isn't published yet, and current injection prices.

Read article
Two oral GLP-1 medicines side by side illustrating different dosing rules
27 August 2026

Orforglipron Dosing vs Rybelsus: How They Differ

How orforglipron (Foundayo) dosing differs from Rybelsus: timing, food rules, titration and forms explained for a UK audience.

Read article
A once-daily oral GLP-1 tablet beside a glass of water on a plain surface
26 August 2026

Orforglipron Side Effects: What the Trials Reported

What side effects were reported in orforglipron (Foundayo) trials? A clear UK guide to the GLP-1 class effect profile, how to manage it, and when to seek help.

Read article
A once-daily oral GLP-1 tablet beside a glass of water on a kitchen worktop
25 August 2026

Orforglipron Weight Loss: The ATTAIN-1 Trial Results

How much weight did people lose on orforglipron? In the Phase 3 ATTAIN-1 trial, participants on 36mg lost 12.4% of body weight over 72 weeks.

Read article
Illustration of a small-molecule GLP-1 receptor agonist tablet and a gut hormone receptor
24 August 2026

How Orforglipron Works: The First Small-Molecule GLP-1 Pill

How orforglipron works: the small-molecule GLP-1 pill explained — mechanism, why it survives digestion, and how it differs from peptide GLP-1 medicines.

Read article
Two oral GLP-1 weight-loss tablets shown side by side on a plain background
23 August 2026

Foundayo vs the Wegovy Tablet: Two Oral GLP-1s

Foundayo (orforglipron) and the Wegovy Tablet (oral semaglutide) are both once-daily oral GLP-1s. Compare mechanism, dosing and how they differ.

Read article
A once-daily oral GLP-1 tablet beside a weekly weight-loss injection pen on a plain background
22 August 2026

Foundayo vs Mounjaro: How the Oral GLP-1 Compares

Foundayo (orforglipron) vs Mounjaro (tirzepatide): how the once-daily GLP-1 pill and the weekly dual-action injection differ in mechanism, dosing and trial data.

Read article
A UK regulatory document alongside an oral weight-loss tablet, illustrating medicine authorisation
21 August 2026

MHRA Authorises Orforglipron: What It Actually Means

The MHRA authorised orforglipron (Foundayo) on 10 August 2026. Here's what a UK marketing authorisation actually means — and why it isn't the same as availability.

Read article
A single once-daily oral tablet next to a glass of water on a plain surface
20 August 2026

Is Foundayo (Orforglipron) Available in the UK?

Foundayo (orforglipron) has a UK marketing authorisation, but that isn't the same as availability. Here's what UK approval actually means in 2026.

Read article
A person checking their eligibility for Mounjaro on a laptop with a notepad and tape measure
18 August 2026

Am I Eligible for Mounjaro? The UK Criteria in Full

Am I eligible for Mounjaro in the UK? The full BMI and health criteria, who it's not suitable for, and how the free consultation checks if it's right for you.

Read article
Check eligibility