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Articles on Mounjaro, Wegovy, GLP-1 side effects, dose escalation, food and lifestyle — and everything else worth knowing about weight-loss medication in the UK.
Starting Foundayo (orforglipron): the 0.8mg and 2.5mg stages
Foundayo (orforglipron) starts at 0.8mg once daily and steps up to 2.5mg. What each stage involves, why titration is gradual, and how to take a small-molecule GLP-1 tablet.
Read article →Will Foundayo Be Available on the NHS?
Will Foundayo (orforglipron) be on the NHS? No NICE date is confirmed. Here's how NHS funding decisions work and what its UK licence means.
Read article →Will Orforglipron Cost Less Than Weight-Loss Injections?
Will orforglipron (Foundayo) cost less than weight-loss injections in the UK? An honest look at what we know, what isn't published yet, and current injection prices.
Read article →Orforglipron Dosing vs Rybelsus: How They Differ
How orforglipron (Foundayo) dosing differs from Rybelsus: timing, food rules, titration and forms explained for a UK audience.
Read article →Orforglipron Side Effects: What the Trials Reported
What side effects were reported in orforglipron (Foundayo) trials? A clear UK guide to the GLP-1 class effect profile, how to manage it, and when to seek help.
Read article →Orforglipron Weight Loss: The ATTAIN-1 Trial Results
How much weight did people lose on orforglipron? In the Phase 3 ATTAIN-1 trial, participants on 36mg lost 12.4% of body weight over 72 weeks.
Read article →How Orforglipron Works: The First Small-Molecule GLP-1 Pill
How orforglipron works: the small-molecule GLP-1 pill explained — mechanism, why it survives digestion, and how it differs from peptide GLP-1 medicines.
Read article →Foundayo vs the Wegovy Tablet: Two Oral GLP-1s
Foundayo (orforglipron) and the Wegovy Tablet (oral semaglutide) are both once-daily oral GLP-1s. Compare mechanism, dosing and how they differ.
Read article →Foundayo vs Mounjaro: How the Oral GLP-1 Compares
Foundayo (orforglipron) vs Mounjaro (tirzepatide): how the once-daily GLP-1 pill and the weekly dual-action injection differ in mechanism, dosing and trial data.
Read article →MHRA Authorises Orforglipron: What It Actually Means
The MHRA authorised orforglipron (Foundayo) on 10 August 2026. Here's what a UK marketing authorisation actually means — and why it isn't the same as availability.
Read article →Is Foundayo (Orforglipron) Available in the UK?
Foundayo (orforglipron) has a UK marketing authorisation, but that isn't the same as availability. Here's what UK approval actually means in 2026.
Read article →Am I Eligible for Mounjaro? The UK Criteria in Full
Am I eligible for Mounjaro in the UK? The full BMI and health criteria, who it's not suitable for, and how the free consultation checks if it's right for you.
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